Detalhe da pesquisa
1.
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Mol Cell
; 83(19): 3558-3573.e7, 2023 10 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37802028
2.
Design, synthesis, and biological evaluation of new raloxifene analogues of improved antagonist activity and endometrial safety.
Bioorg Chem
; 106: 104482, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33272706
3.
Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.
Molecules
; 27(1)2021 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35011476
4.
Design, synthesis and anti-HBV activity evaluation of new substituted imidazo[4,5-b]pyridines.
Bioorg Chem
; 98: 103580, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32005482
5.
Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues.
Molecules
; 25(19)2020 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33022923
6.
Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives.
Molecules
; 25(19)2020 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33049986
7.
Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors.
Molecules
; 25(16)2020 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32824311
8.
Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines.
Chem Pharm Bull (Tokyo)
; 65(1): 66-81, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28049917
9.
The discovery of new cytotoxic pyrazolopyridine derivatives.
Bioorg Med Chem Lett
; 26(21): 5229-5233, 2016 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27720292
10.
Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter.
Bioorg Med Chem
; 24(22): 5941-5952, 2016 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27720327
11.
Synthesis and antiproliferative activity of some novel benzo-fused imidazo[1,8]naphthyridinones.
Bioorg Med Chem Lett
; 25(13): 2621-3, 2015 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25998504
12.
Synthesis of new nebularine analogues and their inhibitory activity against adenosine deaminase.
Chem Pharm Bull (Tokyo)
; 63(2): 134-42, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25748785
13.
One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
STAR Protoc
; 5(1): 102929, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38460134
14.
Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values.
Sci Rep
; 13(1): 11893, 2023 07 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37482547
15.
Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer.
Pharmaceutics
; 15(3)2023 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36986648
16.
Novel H2S-Releasing Bifunctional Antihistamine Molecules with Improved Antipruritic and Reduced Sedative Actions.
J Med Chem
; 66(14): 9607-9621, 2023 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37409873
17.
Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles.
Eur J Med Chem
; 261: 115804, 2023 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37729693
18.
Hydrolytic Activity of Mitochondrial F1FO-ATP Synthase as a Target for Myocardial Ischemia-Reperfusion Injury: Discovery and In Vitro and In Vivo Evaluation of Novel Inhibitors.
J Med Chem
; 66(22): 15115-15140, 2023 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37943012
19.
Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.
J Med Chem
; 65(19): 13305-13327, 2022 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36173355
20.
Discovery of a High Affinity Adenosine A1/A3 Receptor Antagonist with a Novel 7-Amino-pyrazolo[3,4-d]pyridazine Scaffold.
ACS Med Chem Lett
; 13(6): 923-934, 2022 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35707146